Author: Bethany
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exchange efficiency and stability of bispecific antibodies
Sheathless CE-MS as a tool for monitoring exchange efficiency and stability of bispecific antibodies Bispecific monoclonal antibodies (BsAbs) are receiving great attention due to their extensive benefits as biopharmaceuticals and their involvement in IgG4 mediated autoimmune diseases. While the production of BsAbs is getting more accessible, their analytical characterization remains challenging. We explored the potential of […]
Development of a Multiplex Bead Assay for the Detection of IgG Antibody
Development of a Multiplex Bead Assay for the Detection of IgG Antibody Responses to Guinea Worm The success of the Guinea Worm (GW) Eradication Program over the past three decades has been tempered by the persistence of GW disease in a few African nations and the potential for a future resurgence in cases. Domestic dogs are now […]
The Role of IgG Subclass in Antibody-Mediated
The Role of IgG Subclass in Antibody-Mediated Protection against Carbapenem-Resistant Klebsiella pneumoniae Monoclonal antibodies (MAbs) have the potential to assist in the battle against multidrug-resistant bacteria such as carbapenem-resistant Klebsiella pneumoniae (CR-Kp). However, the characteristics by which these antibodies (Abs) function, such as the role of antibody subclass, must be determined before such modalities can be carried from […]