exchange efficiency and stability of bispecific antibodies

Sheathless CE-MS as a tool for monitoring exchange efficiency and stability of bispecific antibodies
Bispecific monoclonal antibodies (BsAbs) are receiving great attention due to their extensive benefits as biopharmaceuticals and their involvement in IgG4 mediated autoimmune diseases. While the production of BsAbs is getting more accessible, their analytical characterization remains challenging.
We explored the potential of sheathless CE-MS for monitoring exchange efficiency and stability of in-house produced bispecific antibodies. Two IgG4 bispecific antibodies with different molecular characteristics were prepared using controlled Fab (Fragment antigen binding) -arm exchange. Separation of BsAbs from their parent monospecific antibodies was achieved using a PEI-coated capillary and acidic background electrolytes permitting reliable assessment of the exchange efficiency.
This was especially valuable for a Fab-glycosylated BsAb where the high glycan heterogeneity resulted in an overlap of masses with the monospecific parent antibody, hindering their discrimination by MS only.
The method showed also good capabilities to monitor the stability of the generated BsAbs under different storage conditions. The levels of degradation products were different for the studied antibodies indicating pronounced differences in stability. Overall, the proposed method represents a useful analytical tool for exchange efficiency and stability studies of bispecific antibodies. This article is protected by copyright. All rights reserved.

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![]() anti-IL-8 (3E4D8) |
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LF-MA30011 | Abfrontier | 100 ul | EUR 448.8 |
Description: Mouse Monoclonal to IL-8 |
![]() Anti-IL-8 antibody |
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STJ97710 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Mouse monoclonal to IL-8. |
![]() Anti-IL-8 antibody |
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STJ97717 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Mouse monoclonal to IL-8. |
![]() Anti-IL-8 antibody |
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STJ97720 | St John's Laboratory | 200 µl | EUR 236.4 |
Description: Mouse monoclonal to IL-8. |
![]() Anti-IL-8 antibody |
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STJ98175 | St John's Laboratory | 100 µl | EUR 280.8 |
Description: Mouse monoclonal to IL-8. |
![]() 1730 8 SNAP-SEAL 8 OZ |
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1730-8 | CORNING | 100/pk | EUR 88.8 |
Description: Disposable Plastic; Plastic Containers |
![]() mAb mouse anti-human IL-8 |
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CT264 | U-CyTech | 0.5 mg | EUR 312 |
![]() IL-8 |
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E5-00004 | EnoGene | 1mg | EUR 1152 |
![]() Anti-IL-8 Monoclonal Antibody |
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A00423-1 | BosterBio | 100ul | EUR 476.4 |
Description: Mouse Monoclonal Antibody for IL-8 Antibody (CXCL8) detection. Tested with IHC in Human, Mouse, Rat. |
![]() Individual Reaction Mix 8 |
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G065-8 | ABM | 200 reactions | EUR 200.4 |
![]() Swine IL-6 Recombinant Protein |
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R00102-8 | BosterBio | 5ug/vial | EUR 310.8 |
Description: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. Swine IL-6 Recombinant Protein is purified interleukin-6 produced in yeast. |
![]() Swine IL-4 Recombinant Protein |
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R00230-8 | BosterBio | 5ug/vial | EUR 310.8 |
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Swine IL-4 Recombinant Protein is purified interleukin-4 produced in yeast. |
![]() Rabbit IL-2 Recombinant Protein |
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R00387-8 | BosterBio | 5ug/vial | EUR 310.8 |
Description: Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. Rabbit IL-2 Recombinant Protein is purified interleukin-2 produced in yeast. |
![]() Swine IL-17A Recombinant Protein |
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R00421-8 | BosterBio | 5ug/vial | EUR 310.8 |
Description: IL-17A is a member of the IL-17 family of cytokines, whose members are involved in numerous immune regulatory functions. IL-17 induces the production of many other cytokines, chemokines, and prostaglandins. Swine IL-17A Recombinant Protein is purified interleukin-17A produced in yeast. |
![]() Human Interleukin-8 (IL-8) Antibody |
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13102-05011 | AssayPro | 150 ug | EUR 248.4 |
![]() Rabbit Polyclonal antibody Anti-CRBN |
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Anti-CRBN | ImmunoStep | 50 µg | EUR 418.8 |
![]() Human IL-8 Antibody |
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33486-05111 | AssayPro | 150 ug | EUR 313.2 |
![]() Human IL-8 Protein |
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abx060803-25ug | Abbexa | 25 ug | EUR 644.4 |
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![]() Human IL-8 Protein |
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abx060804-25ug | Abbexa | 25 ug | EUR 644.4 |
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![]() Recombinant Human IL-8 |
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P0180 | FN Test | 100ug | EUR 626.83 |
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Description: Recombinant Human protein for IL-8 |
![]() IL-8/CXCL8, Human |
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HY-P7224 | MedChemExpress | 50ug | EUR 596.4 |
![]() Recombinant Human IL-8 |
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SJB05-01 | Amyotop | 25µg/vial | EUR 342 |
![]() Ovine IL-1 beta Recombinant Protein |
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R00101-8 | BosterBio | 5ug/vial | EUR 310.8 |
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Ovine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast. |
![]() Sprint™ 8 Clinical Centrifuge with 8 x 15ml fixed angle rotor, 115V |
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C5000-8 | Benchmark Scientific | 1 each | EUR 537.8 |
![]() Human THSD7a ELISA kit |
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8-E01A2155 | BlueGene |
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Description: A competitive ELISA for quantitative measurement of Human THSD7a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
![]() Anti-bovine IL-8 (CXCL8) antibody |
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STJ15100008 | St John's Laboratory | 250 µg | EUR 403.2 |
Description: These monoclonal antibodies enable sensitive and specific detection of bovine IL-8 in ELISpot. |
![]() Anti-bovine IL-8 (CXCL8) antibody |
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STJ15100009 | St John's Laboratory | 250 µg | EUR 403.2 |
Description: This monoclonal antibody enables sensitive and specific detection of bovine IL-8 in ELISA. |
![]() IL-8 Inhibitor |
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5-01378 | CHI Scientific | 4 x 5mg | Ask for price |
![]() IL-8 Antibody |
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BF0238 | Affbiotech | 200ul | EUR 540 |
![]() CXCL8/IL-8 |
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E21-C97 | EnoGene | 10ug | EUR 411.6 |
![]() CXCL8/IL-8 |
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GT15156 | Neuromics | 100 ug | EUR 631.2 |
![]() IL-8 Inhibitor |
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H-2268.0001 | Bachem | 1.0mg | EUR 200.4 |
Description: Sum Formula: C45H66N18O7S; CAS# [138559-60-1] net |
![]() IL-8 Inhibitor |
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H-2268.0005 | Bachem | 5.0mg | EUR 691.2 |
Description: Sum Formula: C45H66N18O7S; CAS# [138559-60-1] net |
![]() IL-8 Inhibitor |
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H-2268.0025 | Bachem | 25.0mg | EUR 2648.4 |
Description: Sum Formula: C45H66N18O7S; CAS# [138559-60-1] net |
![]() Bovine(IL-8) |
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QY-E60063 | Qayee Biotechnology | 96T | EUR 511.2 |
![]() IL-8 Antibody |
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R30420 | NSJ Bioreagents | 100 ug | EUR 419 |
![]() IL-8 Antibody |
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R31932 | NSJ Bioreagents | 100 ug | EUR 419 |
![]() IL-8 Antibody |
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F51235-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 165 |
![]() IL-8 Antibody |
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F51235-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 379 |
![]() IL-8 Antibody |
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5149-100 | Biovision | each | EUR 405.6 |
![]() IL-8, Interleukin-8, monkey |
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RC222-19 | Bio Basic | 5ug | EUR 125.26 |
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![]() Human Interleukin 8, IL-8 ELISA KIT |
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CSB-E04641h-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Quantitative sandwich ELISA kit for measuring Human Interleukin 8, IL-8 in samples from serum, cell culture supernates, saliva, urine, cerebrospinalfluid (CSF), tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
![]() Human Interleukin 8, IL-8 ELISA KIT |
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1-CSB-E04641h | Cusabio |
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Description: Quantitative sandwich ELISA kit for measuring Human Interleukin 8, IL-8 in samples from serum, cell culture supernates, saliva, urine, cerebrospinalfluid(CSF), tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
![]() Human Interleukin 8(IL-8)ELISA Kit |
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GA-E0129HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
![]() Human Interleukin 8(IL-8)ELISA Kit |
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GA-E0129HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
![]() Human Interleukin 8,IL-8 ELISA KIT |
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201-12-0090 | SunredBio | 96 tests | EUR 528 |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
![]() Human Interleukin 8 (IL-8) CLIA Kit |
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abx195916-96tests | Abbexa | 96 tests | EUR 990 |
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![]() Human Interleukin-8 (IL-8) ELISA Kit |
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LF-EK60006 | Abfrontier | 1×96T | EUR 948 |
![]() Human IL-8(Interleukin 8) ELISA Kit |
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EH0205 | FN Test | 96T | EUR 571.5 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
![]() Human Interleukin 8(IL-8)ELISA Kit |
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QY-E04259 | Qayee Biotechnology | 96T | EUR 433.2 |
![]() Human IL-8 ELISA kit |
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CT212A | U-CyTech | 5-plate | EUR 554.4 |
![]() Human IL-8 ELISA Kit |
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EHI0063 | Abclonal | 96Tests | EUR 625.2 |
![]() Human IL-8 ELISA kit |
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LF-EK50165 | Abfrontier | 1×96T | EUR 777.6 |
![]() human IL-8 His tag |
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E410A07-100 | EnoGene | 100μg | EUR 1152 |
![]() IL-8/CXCL8, 72a.a., Human |
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HY-P7380 | MedChemExpress | 50ug | EUR 596.4 |
![]() rec Endothelial IL-8 (human) |
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H-3742.0010 | Bachem | 10.0µg | EUR 340.8 |
Description: Sum Formula: C397H644N114O111S4; CAS# [142298-01-9] |
![]() rec Endothelial IL-8 (human) |
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H-3742.0050 | Bachem | 50.0µg | EUR 1167.6 |
Description: Sum Formula: C397H644N114O111S4; CAS# [142298-01-9] |
![]() rec Monocyte IL-8 (human) |
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H-9625.0005 | Bachem | 5.0µg | EUR 194.4 |
Description: Sum Formula: C372H600N106O106S4; CAS# [142298-00-8] |
![]() rec Monocyte IL-8 (human) |
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H-9625.0025 | Bachem | 25.0µg | EUR 457.2 |
Description: Sum Formula: C372H600N106O106S4; CAS# [142298-00-8] |
![]() IL-8 ELISA KIT|Human |
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EF003990 | Lifescience Market | 96 Tests | EUR 826.8 |
![]() Recombinant Human IL-8 Protein |
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RP00052 | Abclonal | 5 μg | EUR 178.8 |
![]() IL-8 (Human) ELISA Kit |
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K4169-100 | Biovision | each | EUR 874.8 |
![]() Bovine Cytokines IL-8(Cytokines IL-8) ELISA Kit |
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QY-E60102 | Qayee Biotechnology | 96T | EUR 511.2 |
![]() Pesticide Mix 8 Containing 15 Compounds in Acetonitrile |
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SPXPR-8 | Scientific Laboratory Supplies | 1ML | EUR 249.66 |
![]() Horse Interleukin 8 (IL-8) ELISA |
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QY-E120050 | Qayee Biotechnology | 96T | EUR 573.6 |
Attenuated Influenza Virions Expressing the SARS-CoV-2 Receptor-Binding Domain Induce Neutralizing Antibodies in Mice
An effective vaccine is essential for controlling the spread of the SARS-CoV-2 virus. Here, we describe an influenza virus-based vaccine for SARS-CoV-2. We incorporated a membrane-anchored form of the SARS-CoV-2 spike receptor binding domain (RBD) in place of the neuraminidase (NA) coding sequence in an influenza virus also possessing a mutation that reduces the affinity of hemagglutinin for its sialic acid receptor.
The resulting ΔNA(RBD)-Flu virus can be generated by reverse genetics and grown to high titers in cell culture. A single-dose intranasal inoculation of mice with ΔNA(RBD)-Flu elicits serum neutralizing antibody titers against SAR-CoV-2 comparable to those observed in humans following natural infection (~1:200).
Furthermore, NA(RBD)-FΔlu itself causes no apparent disease in mice. It might be possible to produce a vaccine similar to ΔNA(RBD)-Flu at scale by leveraging existing platforms for the production of influenza vaccines.
Human monoclonal anti‑TLR4 antibody negatively regulates lipopolysaccharide‑induced inflammatory responses in mouse macrophages
- Previous studies have revealed that activation of the Toll‑like receptor 4 (TLR4)‑mediated proinflammatory signaling pathway plays an important role in acute inflammation, sepsis and chronic inflammatory disorders.
- Moreover, TLR4 significantly contributes to lipopolysaccharide (LPS)‑induced immune response. Thus, modulation of the TLR4 pathway is an important strategy to specifically target these pathologies.
- The aim of the present study was to develop a complete human anti‑TLR4 IgG2 antibody by screening human TLR4 Fab from a phage‑display library and integrating it with constant regions of the heavy chain of human IgG2 via antibody engineering. ELISA, a BLItz system and fluorescence‑activated cell sorting were used to assess its affinity.
- Furthermore, mouse‑derived peritoneal macrophages were treated with human anti‑TLR4 IgG2 and induced with LPS in vitro. Reverse transcription‑quantitative PCR and western blotting were used to determine mRNA expression levels of cytokines and phosphorylation levels of signaling pathways, respectively.
- It was found that human anti‑TLR4 IgG2 bound to TLR4 with a high affinity of 8.713×10‑10 M, and that preincubation with anti‑TLR4 IgG2 inhibited the LPS‑induced production of tumor necrosis factor‑α, interferon‑β and interleukin‑6 mRNA expression levels in mouse peritoneal macrophages.
- It was also demonstrated that human anti‑TLR4 IgG2 inhibited LPS‑induced TLR4 signaling by reducing the phosphorylation of the NF‑κB, mitogen‑activated protein kinase and interferon regulatory factor 3 signaling pathways.
- In addition, human anti‑TLR4 IgG2 protected mice from LPS challenge with a survival rate of 40% and also significantly increased the survival time in the cecal ligation and puncture model. Therefore, it was speculated that human anti‑TLR4 IgG2 plays a protective role against sepsis‑associated injury and is potentially applicable for the treatment of infection‑associated immune dysfunction.
![]() Anti-KIR2DL4 antibody |
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STJ114702 | St John's Laboratory | 100 µl | EUR 332.4 |
Description: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternate alleles of this gene are represented on multiple alternate reference loci (ALT_REF_LOCs). Alternative splicing results in multiple transcript variants, some of which may not be annotated on the primary reference assembly. |
![]() KIR2DL4 Antibody |
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DF13591 | Affbiotech | 100ul | EUR 420 |
![]() KIR2DL4 antibody |
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70R-2365 | Fitzgerald | 50 ug | EUR 560.4 |
Description: Rabbit polyclonal KIR2DL4 antibody raised against the middle region of KIR2DL4 |
![]() KIR2DL4 siRNA |
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20-abx921662 | Abbexa |
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![]() Rabbit Polyclonal antibody Anti-CRBN |
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Anti-CRBN | ImmunoStep | 50 µg | EUR 418.8 |
![]() Human KIR2DL4 shRNA Plasmid |
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20-abx952576 | Abbexa |
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![]() Human KIR2DL4 ELISA KIT |
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ELI-21303h | Lifescience Market | 96 Tests | EUR 988.8 |
![]() KIR2DL4 Recombinant Protein (Human) |
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RP017041 | ABM | 100 ug | Ask for price |
![]() KIR2DL4 cloning plasmid |
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CSB-CL857457HU-10ug | Cusabio | 10ug | EUR 279.6 |
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Description: A cloning plasmid for the KIR2DL4 gene. |
![]() KIR2DL4 Recombinant Protein |
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91-290 | ProSci | 0.05 mg | EUR 556.8 |
Description: Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16. |
![]() KIR2DL4 Rabbit pAb |
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A12836-100ul | Abclonal | 100 ul | EUR 369.6 |
![]() KIR2DL4 Rabbit pAb |
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A12836-200ul | Abclonal | 200 ul | EUR 550.8 |
![]() KIR2DL4 Rabbit pAb |
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A12836-20ul | Abclonal | 20 ul | EUR 219.6 |
![]() KIR2DL4 Rabbit pAb |
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A12836-50ul | Abclonal | 50 ul | EUR 267.6 |
![]() KIR2DL4 Blocking Peptide |
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33R-9831 | Fitzgerald | 100 ug | EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of KIR2DL4 antibody, catalog no. 70R-2365 |
![]() KIR2DL4 Polyclonal Antibody |
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27806-100ul | SAB | 100ul | EUR 302.4 |
![]() KIR2DL4 Polyclonal Antibody |
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27806-50ul | SAB | 50ul | EUR 224.4 |
![]() pOTB7-KIR2DL4 Plasmid |
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PVTB00348 | Lifescience Market | 2 ug | EUR 427.2 |
![]() KIR2DL4 ORF Vector (Human) (pORF) |
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ORF005681 | ABM | 1.0 ug DNA | EUR 114 |
![]() KIR2DL4 Polyclonal Conjugated Antibody |
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C27806 | SAB | 100ul | EUR 476.4 |
![]() pEGFP-flag-KIR2DL4 Plasmid |
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PVTB00348-2a | Lifescience Market | 2 ug | EUR 427.2 |
![]() KIR2DL4 sgRNA CRISPR Lentivector set (Human) |
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K1150301 | ABM | 3 x 1.0 ug | EUR 406.8 |
![]() Polyclonal Goat anti-GST α-form |
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GST-ANTI-1 | Detroit R&D | 50 uL | EUR 336 |
![]() Polyclonal Goat anti-GST μ-form |
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GST-ANTI-2 | Detroit R&D | 50 uL | EUR 336 |
![]() Polyclonal Goat anti-GST p-form |
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GST-ANTI-3 | Detroit R&D | 50 uL | EUR 336 |
![]() KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 Antibody |
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1-CSB-PA205578 | Cusabio |
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Description: A polyclonal antibody against KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4. Recognizes KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200 |
![]() KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 Antibody |
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1-CSB-PA246816 | Cusabio |
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Description: A polyclonal antibody against KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4. Recognizes KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:50-1:100 |
![]() KIR2DL3 / KIR2DL1 / KIR2DL4 / KIR2DS4 Antibody |
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20-abx210854 | Abbexa |
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![]() KIR2DL3 / KIR2DL1 / KIR2DL4 / KIR2DS4 Antibody |
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20-abx339417 | Abbexa |
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![]() Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His) |
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C310-10ug | Novoprotein | 10ug | EUR 157.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
![]() Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His) |
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C310-1mg | Novoprotein | 1mg | EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
![]() Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His) |
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C310-500ug | Novoprotein | 500ug | EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
![]() Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His) |
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C310-50ug | Novoprotein | 50ug | EUR 327.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
![]() KIR2DL4 sgRNA CRISPR Lentivector (Human) (Target 1) |
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K1150302 | ABM | 1.0 ug DNA | EUR 184.8 |
![]() KIR2DL4 sgRNA CRISPR Lentivector (Human) (Target 2) |
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K1150303 | ABM | 1.0 ug DNA | EUR 184.8 |
![]() KIR2DL4 sgRNA CRISPR Lentivector (Human) (Target 3) |
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K1150304 | ABM | 1.0 ug DNA | EUR 184.8 |
![]() KIR2DL4 Protein Vector (Human) (pPB-C-His) |
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PV022721 | ABM | 500 ng | EUR 394.8 |
![]() KIR2DL4 Protein Vector (Human) (pPB-N-His) |
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PV022722 | ABM | 500 ng | EUR 394.8 |
![]() KIR2DL4 Protein Vector (Human) (pPM-C-HA) |
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PV022723 | ABM | 500 ng | EUR 394.8 |
![]() KIR2DL4 Protein Vector (Human) (pPM-C-His) |
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PV022724 | ABM | 500 ng | EUR 394.8 |
![]() Recombinant Human KIR2DL4 Protein, His, Insect-1ug |
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QP12489-1ug | EnQuireBio | 1ug | EUR 186 |
![]() Recombinant Human KIR2DL4 Protein, His, Insect-50ug |
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QP12489-50ug | EnQuireBio | 50ug | EUR 1513.2 |
![]() Recombinant Human KIR2DL4 Protein, His, Insect-5ug |
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QP12489-5ug | EnQuireBio | 5ug | EUR 241.2 |
![]() KIR2DL4 3'UTR GFP Stable Cell Line |
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TU061796 | ABM | 1.0 ml | EUR 1825.2 |
![]() KIR2DL4 3'UTR Luciferase Stable Cell Line |
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TU011796 | ABM | 1.0 ml | EUR 1825.2 |
![]() KIR2DL4 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
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K1150305 | ABM | 3 x 1.0 ug | EUR 451.2 |
![]() Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Antibody |
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abx145740-100ug | Abbexa | 100 ug | EUR 469.2 |
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![]() KIR2DL4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
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K1150306 | ABM | 1.0 ug DNA | EUR 200.4 |
![]() KIR2DL4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
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K1150307 | ABM | 1.0 ug DNA | EUR 200.4 |
![]() KIR2DL4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
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K1150308 | ABM | 1.0 ug DNA | EUR 200.4 |
![]() KIR2DL4 Killer Cell Immunoglobulin-Like Receptor, 2 Domains Long Cytoplasmic Tail 4 Human Recombinant Protein |
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PROTQ99706 | BosterBio | Regular: 5ug | EUR 380.4 |
Description: KIR2DL4 Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 458 amino acids (24-242 a.a.) and having a molecular mass of 51kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). KIR2DL4 is expressed with a 239 amino acids hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.  |
![]() Anti-Human IgG |
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DB-173-0.1 | DB Biotech | 100 μl | EUR 254.4 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-Human IgG |
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DB-173-0.2 | DB Biotech | 200 μl | EUR 357.6 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-Human IgG |
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DB-173-0.5 | DB Biotech | 500 μl | EUR 460.8 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-Human IgG |
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DB-173-1 | DB Biotech | 1 ml | EUR 735.6 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-Human IgG |
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DB-173-RTU-15 | DB Biotech | 15 ml | EUR 426 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Anti-Human IgG |
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DB-173-RTU-7 | DB Biotech | 7 ml | EUR 277.2 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Anti-Human IgG |
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DB-174-0.1 | DB Biotech | 100 μl | EUR 254.4 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-Human IgG |
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DB-174-0.2 | DB Biotech | 200 μl | EUR 357.6 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-Human IgG |
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DB-174-0.5 | DB Biotech | 500 μl | EUR 460.8 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-Human IgG |
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DB-174-1 | DB Biotech | 1 ml | EUR 735.6 |
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated |
![]() Anti-Human IgG |
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DB-174-RTU-15 | DB Biotech | 15 ml | EUR 426 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Anti-Human IgG |
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DB-174-RTU-7 | DB Biotech | 7 ml | EUR 277.2 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Anti-Human IgG |
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DB173RTU-15 | DB Biotech | 15 ml | EUR 426 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Anti-Human IgG |
|||
DB173RTU-7 | DB Biotech | 7 ml | EUR 277.2 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Anti-Human IgG |
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DB174RTU-15 | DB Biotech | 15 ml | EUR 426 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() Anti-Human IgG |
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DB174RTU-7 | DB Biotech | 7 ml | EUR 277.2 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() anti-human CCR1 |
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20R-3028 | Fitzgerald | 200 ug | EUR 704.4 |
Description: Goat anti-human CCR1 antibody |
![]() anti-human RecQL4 |
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AR05-PA0007 | Abfrontier | 100 ul | EUR 400.8 |
Description: Rabbit polyclonal to human RecQL4 |
![]() anti-human Albumin |
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LF-PA10001 | Abfrontier | 100 ug | EUR 483.6 |
Description: Rabbit polyclonal to human Albumin |
![]() Goat anti-Human anti-thrombin polyclonal antibody |
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CABT-L487 | Creative Diagnostics | 500ug | EUR 858 |
![]() Sheep anti-Human anti-thrombin polyclonal antibody |
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CABT-L488 | Creative Diagnostics | 500ug | EUR 795.6 |
![]() Sheep anti-Human anti-thrombin polyclonal antibody |
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CABT-L489 | Creative Diagnostics | 100ug | EUR 795.6 |
![]() Sheep anti-Human anti-thrombin polyclonal antibody |
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CABT-L490 | Creative Diagnostics | 100ug | EUR 795.6 |
![]() Sheep anti-Human anti-thrombin polyclonal antibody |
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CABT-L491 | Creative Diagnostics | 100ug | EUR 795.6 |
![]() Human anti AMPH(anti amphiphysin) ELISA Kit |
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EH2621 | FN Test | 96T | EUR 628.92 |
|
|||
Description: Method of detection: Sandwich ELISA, Double Antigen;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
![]() Human anti-TPO(anti-thrombopoietin) ELISA Kit |
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EH4147 | FN Test | 96T | EUR 628.92 |
|
|||
Description: Method of detection: Sandwich ELISA, Double Antigen;Reacts with: Homo sapiens ;Sensitivity: 0.938 ng/ml |
![]() Anti-Procalcitonin antibody *Mouse anti-human, monoclonal * |
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V100125 | AAT Bioquest | 50 ug | EUR 367.2 |
|
![]() Anti-Procalcitonin antibody *Mouse anti-human, monoclonal * |
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V100126 | AAT Bioquest | 1 mg | EUR 471.6 |
|
![]() Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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AEA465Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 6777.36 |
|
|||
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
![]() Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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AEA465Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 663.31 |
|
|||
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
![]() Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
|||
AEA465Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 896.16 |
|
|||
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
![]() Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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AEA465Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3672.72 |
|
|||
Description: This is Competitive Enzyme-linked immunosorbent assay for Antibody Detection.detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in serum, plasma and other biological fluids. |
![]() Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) ELISA Kit |
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4-AEA465Hu | Cloud-Clone |
|
|
|
|||
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Anti-Anti-Sperm Antibody Antibody (Anti-AsAb) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
![]() Anti-human CD47 mAb |
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CM096-100ug | SAB | 100ug | EUR 416.4 |
![]() Anti-human CD47 mAb |
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CM096-25ug | SAB | 25ug | EUR 242.4 |
![]() Anti-human CD45 mAb |
|||
CM100-100ug | SAB | 100ug | EUR 146.4 |
![]() Anti-human CD45 mAb |
|||
CM100-25ug | SAB | 25ug | EUR 103.2 |
![]() Goat Anti-Human IgA |
|||
C020242-1mg | Unibiotest | 1mg | EUR 272.4 |
![]() Goat Anti-Human IgA |
|||
C020242-50mg | Unibiotest | 50mg | EUR 3162 |
![]() Anti-Human IgG:HRP Conjugate |
|||
F163 | Cygnus Technologies | 12 ml | EUR 585.6 |
|
|||
Description: Anti-Human IgG:HRP Conjugate by Cygnus Technologies is available in Europe via Gentaur. |
![]() anti- Human IgA antibody |
|||
FNab04075 | FN Test | 100µg | EUR 702 |
|
|||
Description: Antibody raised against Human IgA |
![]() anti- Human IgA antibody |
|||
FNab04076 | FN Test | 100µg | EUR 702 |
|
|||
Description: Antibody raised against Human IgA |
![]() anti- Human IgG antibody |
|||
FNab04077 | FN Test | 100µg | EUR 702 |
|
|||
Description: Antibody raised against Human IgG |
![]() Goat anti Human IgE |
|||
70R-IG015 | Fitzgerald | 1 mg | EUR 418.8 |
Description: Affinity purified Goat anti Human IgE antibody |
![]() Goat anti Human IgG |
|||
70C-CR6047GAP | Fitzgerald | 1 mg | EUR 178.8 |
Description: Affinity purified Goat anti Human IgG antibody |
![]() Goat anti Human IgM |
|||
70-B9022GA00-A0 | Fitzgerald | 5 mg | EUR 230.4 |
Description: Goat anti Human IgM antibody |
![]() Goat anti Human IgG |
|||
41C-CB0957 | Fitzgerald | 5 mg | EUR 415.2 |
Description: Goat anti Human IgG secondary antibody |
![]() Goat anti Human IgG |
|||
41C-CB0972 | Fitzgerald | 2 mg | EUR 316.8 |
Description: Goat anti Human IgG secondary antibody |