Human Natural Antibodies Recognizing

enviroshieldproducts

Human Natural Antibodies Recognizing Glycan Galβ1-3GlcNAc (Le C)

The level of human natural antibodies of immunoglobulin M isotype against LeC in patients with breast cancer is lower than in healthy women. The epitope specificity of these antibodies has been characterized using a printed glycan array and enzyme-linked immunosorbent assay (ELISA), the antibodies being isolated from donors’ blood using LeC-Sepharose (LeC is Galβ1-3GlcNAcβ).
The isolated antibodies recognize the disaccharide but do not bind to glycans terminated with LeC, which implies the impossibility of binding to regular glycoproteins of non-malignant cells. The avidity (as dissociation constant value) of antibodies probed with a multivalent disaccharide is 10-9 M; the nanomolar level indicates that the concentration is sufficient for physiological binding to the cognate antigen.
Testing of several breast cancer cell lines showed the strongest binding to ZR 75-1. Interestingly, only 7% of the cells were positive in a monolayer with a low density, increasing up to 96% at highest density.
The enhanced interaction (instead of the expected inhibition) of antibodies with ZR 75-1 cells in the presence of Galβ1-3GlcNAcβ disaccharide, indicates that the target epitope of anti-LeC antibodies is a molecular pattern with a carbohydrate constituent rather than a glycan.
enviroshieldproducts
enviroshieldproducts

Rabbit anti Human Resistin (a.a. 79-90)

MBS315626-5x01mg 5x0.1mg
EUR 4025

Anti- Resistin Human -BIOTIN Antibody

GWB-98D44D 0.05 mg Ask for price

Anti-Human Resistin

GWB-BIG87E 500ug Ask for price

Anti-Human Resistin

MBS550711-01mg 0.1mg
EUR 260

Anti-Human Resistin

MBS550711-02mg 0.2mg
EUR 335

Human Resistin

90233-A 5 µg
EUR 130
Description: Recombinant Resistin is a disulfide-linked homodimeric protein consisting of two 93 amino acid residues, and migrates as an approximately 20 kDa protein under non-reducing conditions and as a 10 kDa protein under reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Resistin mature chain was expressed in E. coli.

Human Resistin

90233-B 25 µg
EUR 205
Description: Recombinant Resistin is a disulfide-linked homodimeric protein consisting of two 93 amino acid residues, and migrates as an approximately 20 kDa protein under non-reducing conditions and as a 10 kDa protein under reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Resistin mature chain was expressed in E. coli.

Human resistin

MBS400069-001mg 0.01mg
EUR 220

Human resistin

MBS400069-005mg 0.05mg
EUR 545

Human resistin

MBS400069-01mg 0.1mg
EUR 770

Human resistin

MBS400069-1mg 1mg
EUR 3830

Human Resistin

MBS692069-0005mg 0.005mg
EUR 300

Human Resistin

MBS692069-0025mg 0.025mg
EUR 450

Human Resistin

MBS692069-5x0025mg 5x0.025mg
EUR 1725

Human Resistin Antibody

32138-05111 150 ug
EUR 215

Human Resistin Antibody

GWB-F7AAE4 0.1 mg Ask for price

Resistin (43-65) (Human) - Antibody

H-028-39 50 μl
EUR 604.8

Resistin (51-108) (Human) - Antibody

H-028-40 50 μl
EUR 604.8

Resistin (43-65) (Human)

028-39 100 μg
EUR 255.96

Resistin (51-108) (Human)

028-40 20 μg
EUR 282.96

Resistin (23-42) (Human)

028-41 100 μg
EUR 214.92

Resistin (25-42) (Human)

028-42 100 μg
EUR 214.92

Mouse Anti-Human Resistin

MBS690775-05mg 0.5mg
EUR 525

Mouse Anti-Human Resistin

MBS690775-5x05mg 5x0.5mg
EUR 2080

Human Resistin (RETN)

1-CSB-EP019573HU
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 10ug
  • 50ug
  • 100ug
  • 200ug
  • 500ug
  • 1MG
Description: Recombinant Human Resistin(RETN) expressed in E.coli

Human resistin antagonist

MBS400115-001mg 0.01mg
EUR 220

Human resistin antagonist

MBS400115-005mg 0.05mg
EUR 545

Human resistin antagonist

MBS400115-01mg 0.1mg
EUR 770

Human resistin antagonist

MBS400115-1mg 1mg
EUR 3830

Anti-Human Resistin Antibody

102-P92G 100 µg
EUR 245.7
Description: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis.

Anti-Human Resistin Antibody

101-M170 500 µg
EUR 246.75
Description: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Recombinant human Resistin is a 19.5 kDa disulfide-linked homodimeric protein composed of two identical 92 amino acid chains linked by a single disulfide bond.

Anti-Human Resistin Antibody

101-M618 100 µg
EUR 399
Description: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis.

Biotinylated Anti-Human Resistin

GWB-BIG87D 1 kit Ask for price

Recombinant Human Resistin

7-01519 5µg Ask for price

Recombinant Human Resistin

7-01520 25µg Ask for price

Recombinant Human Resistin

7-01521 1mg Ask for price

Recombinant Human Resistin

cyt-456-1mg 1mg
EUR 4680

Recombinant Human Resistin

cyt-456-25g 25µg
EUR 145

Recombinant Human Resistin

cyt-456-5g 5µg
EUR 60

Recombinant Human Resistin

MBS1410331-002mgEColi 0.02mg(E-Coli)
EUR 255

Recombinant Human Resistin

MBS1410331-01mgEColi 0.1mg(E-Coli)
EUR 405

Recombinant Human Resistin

MBS1410331-1mgEColi 1mg(E-Coli)
EUR 1425

Recombinant Human Resistin

MBS1410331-5x1mgEColi 5x1mg(E-Coli)
EUR 6215

Recombinant Human Resistin

MBS142332-0005mg 0.005mg
EUR 240

Recombinant Human Resistin

MBS142332-0025mg 0.025mg
EUR 310

Recombinant Human Resistin

MBS142332-1mg 1mg
EUR 4895

Recombinant Human Resistin

MBS142332-5x1mg 5x1mg
EUR 21695

RECOMBINANT HUMAN RESISTIN

GWB-F4A137 0.02 mg Ask for price

Human Resistin Recombinant

MBS553192-0005mg 0.005mg
EUR 165

Human Resistin Recombinant

MBS553192-0025mg 0.025mg
EUR 245

RECOMBINANT HUMAN RESISTIN

MBS232425-0025mg 0.025mg
EUR 510

RECOMBINANT HUMAN RESISTIN

MBS232425-5x0025mg 5x0.025mg
EUR 2130

Recombinant Human Resistin

MBS7611410-005mg 0.05mg
EUR 345

Recombinant Human Resistin

MBS7611410-02mg 0.2mg
EUR 635

Recombinant Human Resistin

MBS7611410-1mg 1mg
EUR 1800

Recombinant Human Resistin

MBS7611410-5x1mg 5x1mg
EUR 6955

Recombinant Human Resistin

MBS9420612-002mg 0.02mg
EUR 285

Recombinant Human Resistin

MBS9420612-01mg 0.1mg
EUR 470

Recombinant Human Resistin

MBS9420612-1mg 1mg
EUR 1785

Recombinant Human Resistin

MBS9420612-5x1mg 5x1mg
EUR 7885

Human Resistin CLIA Kit

MBS8425884-INQUIRE INQUIRE Ask for price

Resistin, recombinant (Human)

028-36 20 μg
EUR 423.36

Resistin, human recombinant

4559-100 each
EUR 874.8

Resistin, human recombinant

4559-1000 each
EUR 6127.2

Resistin, human recombinant

4559-25 each
EUR 307.2

Resistin (Recombinant) Human

GWB-8EE40A 0.025 mg Ask for price

Resistin Human Recombinant

rAP-0727 Inquiry Ask for price

Human Resistin ELISA kit

55R-1714 1 kit
EUR 717
Description: ELISA kit for the detection of Human Resistin in the research laboratory

Human Resistin ELISA kit

55R-2127 96 tests
EUR 825
Description: ELISA Kit for detection of Resistin in the research laboratory

Human Resistin ELISA kit

55R-E50 96 wells
EUR 715
Description: ELISA kit for the detection of Human Resistin in the research laboratory

human Resistin ELISA KIT

201-12-0339 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Resistin ELISA Kit

CEK1754 96T
EUR 538
Description: Sandwich ELKSA for quantitative detection of Human Resistin concentrations.

Human Resistin ELISA KIT

CSB-E06884h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Resistin in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Resistin ELISA KIT

CSB-E06884h-48T 48T
EUR 241.31
Description: Homo sapiens (Human)

Human Resistin ELISA KIT

1-CSB-E06884h
  • Ask for price
  • Ask for price
  • Ask for price
  • 5 plates of 96 wells each
  • 10 plates of 96 wells each
  • 1 plate of 96 wells
Description: Quantitativesandwich ELISA kit for measuring Human Resistin in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Resistin ELISA KIT

CSB-E06884h-96T 96T
EUR 371.25
Description: Homo sapiens (Human)

human Resistin ELISA KIT

CN-04165H1 96T
EUR 530.4

human Resistin ELISA KIT

CN-04165H2 48T
EUR 351.6

Human Resistin ELISA kit

E01A7519 96T
EUR 700
Description: ELISA

Human Resistin ELISA kit

E01R0351-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Resistin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Resistin ELISA kit

E01R0351-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Resistin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Resistin ELISA kit

E01R0351-48wellsplate 48 wells plate
EUR 280

Human Resistin ELISA kit

E01R0351-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Resistin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Resistin ELISA kit

E01R0351-96wellsplate 96 wells plate
EUR 405

Human Resistin ELISA Kit

K0331199 96well
EUR 271
Description: https://komabiotech.co.kr/labiskoma/datasheet/K0331199.pdf

Human Resistin ELISA Kit

E16HE0035 96T
EUR 833.33

Human Resistin ELISA KIT

E16HE0035-048 48 wells
EUR 295

Human Resistin ELISA KIT

E16HE0035-096 96 wells
EUR 395

Human Resistin ELISA Kit

EHR0358 96Tests
EUR 625.2

Human Resistin ELISA Kit

EK2351 96 tests
EUR 497

Human Resistin ELISA Kit

E28L0045 96T
EUR 666.67

Human Resistin ELISA KIT

EKC40240-48T 48T
EUR 412.02

Human Resistin ELISA KIT

EKC40240-5x96T 5x96T
EUR 2795.85

Human Resistin ELISA KIT

EKC40240-96T 96T
EUR 588.6

Human Resistin ELISA kit

E22-HC136.48 48T
EUR 295
Description: 8pg/ml

Human Resistin ELISA kit

E22-HC136.96 96T
EUR 395
Description: 8pg/ml

Human Resistin ELISA KIT

E42EH-93 96T/48T
EUR 795

Human Resistin ELISA Kit

GWB-ZZD207 1x96 well plate Ask for price

Human Resistin ELISA Kit

GWB-SKR059 96 Tests Ask for price

Human Resistin ELISA kit

LF-EK50441 1×96T
EUR 790.8

Human Resistin ELISA Kit

LF-EK70021 1×96T
EUR 625.2

Human Resistin ELISA Kit

MBS008924-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Resistin ELISA Kit

MBS008924-48StripWells 48-Strip-Wells
EUR 550

Human Resistin ELISA Kit

MBS008924-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Resistin ELISA Kit

MBS008924-96StripWells 96-Strip-Wells
EUR 765

Human Resistin ELISA Kit

MBS3800505-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Resistin ELISA Kit

MBS3800505-48StripWells 48-Strip-Wells
EUR 550

Human Resistin ELISA Kit

MBS3800505-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Resistin ELISA Kit

MBS3800505-96StripWells 96-Strip-Wells
EUR 765

Human Resistin ELISA Kit

MBS2885825-10x96StripWells 10x96-Strip-Wells
EUR 3290

Human Resistin ELISA Kit

MBS2885825-48StripWells 48-Strip-Wells
EUR 340

Human Resistin ELISA Kit

MBS2885825-5x96StripWells 5x96-Strip-Wells
EUR 1800

Human Resistin ELISA Kit

MBS2885825-96StripWells 96-Strip-Wells
EUR 435

human Resistin ELISA Kit

MBS700822-10x96StripWells 10x96-Strip-Wells
EUR 4795

human Resistin ELISA Kit

MBS700822-24StripWellsLIMIT1 24-Strip-Wells(LIMIT1)
EUR 275

human Resistin ELISA Kit

MBS700822-48StripWells 48-Strip-Wells
EUR 415

human Resistin ELISA Kit

MBS700822-5x96StripWells 5x96-Strip-Wells
EUR 2515

human Resistin ELISA Kit

MBS700822-96StripWells 96-Strip-Wells
EUR 580

Human Resistin ELISA Kit

MBS720386-48StripWellsCompetitive 48-Strip-Wells-(Competitive)
EUR 485

Human Resistin ELISA Kit

MBS720386-48StripWellsSandwich 48-Strip-Wells-(Sandwich)
EUR 485

Human Resistin ELISA Kit

MBS720386-5x96StripWellsCompetitive 5x96-Strip-Wells-(Competitive)
EUR 3020

Human Resistin ELISA Kit

MBS720386-96StripWellsCompetitive 96-Strip-Wells-(Competitive)
EUR 690

Human Resistin ELISA Kit

MBS720386-96StripWellsSandwich 96-Strip-Wells-(Sandwich)
EUR 690

Human Resistin ELISA Kit

MBS762836-10x96StripWells 10x96-Strip-Wells
EUR 3900

Human Resistin ELISA Kit

MBS762836-48StripWells 48-Strip-Wells
EUR 340

Human Resistin ELISA Kit

MBS762836-5x96StripWells 5x96-Strip-Wells
EUR 2045

Human Resistin ELISA Kit

MBS762836-96StripWells 96-Strip-Wells
EUR 455

Human Resistin ELISA Kit

MBS824773-5x96Tests 5x96Tests
EUR 2755

Human Resistin ELISA Kit

MBS824773-96Tests 96Tests
EUR 620

Human Resistin ELISA Kit

MBS8244688-5x96Tests 5x96Tests
EUR 2755

Human Resistin ELISA Kit

MBS8244688-96Tests 96Tests
EUR 620

Human Resistin ELISA Kit

MBS824892-5x96Tests 5x96Tests
EUR 2755

Human Resistin ELISA Kit

MBS824892-96Tests 96Tests
EUR 620

Human Resistin ELISA KIT

MBS8506135-48Wells 48Wells
EUR 390

Human Resistin ELISA KIT

MBS8506135-5x96Wells 5x96Wells
EUR 2275

Human Resistin ELISA KIT

MBS8506135-96Wells 96Wells
EUR 495

Human Resistin ELISA Kit

MBS8579201-48Tests 48Tests
EUR 390

Human Resistin ELISA Kit

MBS8579201-5x96Tests 5x96Tests
EUR 2275

Targeted bottom-up characterization of recombinant monoclonal antibodies by multi-dimensional LC/MS

  • On-line bottom-up approaches have recently emerged as promising alternatives to standard off-line processes for char-acterizing post-translational modifications (PTMs) of therapeutic monoclonal antibodies (mAbs).
  • The benefits of on-line processing include reductions in required sample amount and sample handling, as well as reducing the overall turnaround time. However, shortening digestion time for the on-line approach of an intact mAb can cause incomplete peptide cleavages, leading to low sequence coverage and poor repeatability of analyses.
  • For the first time, we describe a novel, automated targeted bottom-up strategy consisting of reducing the complexity of intact mAb by digesting the product into small ~25 kDa fragments, followed by an on-line peptide mapping analysis of each fragment. For this pur-pose, a 4D-LC/MS method was developed using a immobilized IdeS-HPLC column as a first dimension (1D) for on-line digestion, followed by a (2D) on-column reversed-phase liquid chromatography (RPLC) for reduction and fragments separation.
  • Then, only one fragment was selected for digestion using a (3D) immobilized trypsin cartridge and finally, the obtained peptides were analyzed by (4D) RPLC-MS. This strategy considerably improved the on-line digestion effi-ciency with higher sequence coverages (LC and HC > 97%), thus allowing various PTMs including oxidation, deami-dation, and isomerization located in the complementarity-determining regions (CDRs), as well as N-glycans present on the Fc/2 fragment, to be monitored with similar sensitivity to those obtained with standard off-line approaches.
  • Additional investigations at a middle-up level were also performed via a 3D-LC/MS approach within the same system, demonstrating the feasibility to achieve a multi-level comprehensive characterization of mAbs.
Monophosphoryl lipid A-induced activation of plasmacytoid dendritic cells enhances the anti-cancer effects of anti-PD-L1 antibodies
Monophosphoryl lipid A (MPLA) is a toll-like receptor 4 ligand that promotes immune activation in mice and humans, without undesired inflammation. Immunotherapy by the combining immune checkpoint blockade and MPLA has shown promising anti-cancer effects in both mice and humans.
In this study, we explored how MPLA enhanced the anti-cancer effects of anti-PD-L1 antibodies (Abs). Anti-cancer immunity induced by the combination of anti-PD-L1 Abs and MPLA failed in CD4 and CD8 cell-depleted mice. Moreover, the combination treatment of anti-PD-L1 Abs and MPLA synergistically enhanced the activation of plasmacytoid dendritic cells (pDCs) in the mouse in vivo, while conventional DCs were not. In addition, mice treated with anti-PD-L1 Abs and MPLA were not protected from B16 melanoma by blockade of interferon-alpha receptor (IFNAR).
The combination of anti-PD-L1 Abs and MPLA also promoted human peripheral blood pDC activation and induced IFN-α-dependent T cell activation. Therefore, these results demonstrate that MPLA enhances anti-PD-L1 Ab-mediated anti-cancer immunity through the activation and IFN-α production of pDCs.

Mouse Anti-Human LEC

MBS690207-05mg 0.5mg
EUR 525

Mouse Anti-Human LEC

MBS690207-5x05mg 5x0.5mg
EUR 2080

Recombinant Human LEC

MBS7608806-005mg 0.05mg
EUR 345

Recombinant Human LEC

MBS7608806-02mg 0.2mg
EUR 635

Recombinant Human LEC

MBS7608806-1mg 1mg
EUR 1800

Recombinant Human LEC

MBS7608806-5x1mg 5x1mg
EUR 6955

Human LEC (CCL16) Recombinant

MBS553045-0005mg 0.005mg
EUR 165

Human LEC (CCL16) Recombinant

MBS553045-0025mg 0.025mg
EUR 245

Recombinant Human LEC (CCL16)

MBS4159662-0025mg 0.025mg
EUR 385

Recombinant Human LEC (CCL16)

MBS4159662-1mg 1(mg)
EUR 4600

Recombinant Human LEC (CCL16)

MBS4159662-5x1mg 5x1mg
EUR 20445

Recombinant Human LEC (CCL16)

Z100325 25 µg
EUR 235
Description: CCL16 is a CC chemokine that specifically attracts lymphocytes, dendritic cells, and monocytes; increases their adhesive properties and has myelosuppressive activity. It is constitutively expressed in liver and is increased by interleukin 10 (IL-10) in activated monocytes. CCL16 is present in human plasma suggesting that it may be active outside hepatic tissue. CCR1, CCR2, CCR5, and CCR8 are the functional receptors of this chemokine.

Recombinant Human LEC (CCL16)

Z100329 1.0 mg
EUR 3900
Description: CCL16 is a CC chemokine that specifically attracts lymphocytes, dendritic cells, and monocytes; increases their adhesive properties and has myelosuppressive activity. It is constitutively expressed in liver and is increased by interleukin 10 (IL-10) in activated monocytes. CCL16 is present in human plasma suggesting that it may be active outside hepatic tissue. CCR1, CCR2, CCR5, and CCR8 are the functional receptors of this chemokine.

Human LEC/CCL16 Antibody Pair Set

ABPR-ZB293 5 plates, 15 plates Ask for price
Description: Quantitative determination of Human LEC/CCL16

Anti-Human LEC/NCC-4 Antibody

102-P51G 100 µg
EUR 245.7
Description: LEC or NCC-4 is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes but not neutrophils. Recombinant human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Anti-Human LEC Goat Polyclonal Antibody

TA328365 100 µg Ask for price

Human LEC/NCC-4 (CCL16)

MBS692056-0005mg 0.005mg
EUR 300

Human LEC/NCC-4 (CCL16)

MBS692056-002mg 0.02mg
EUR 450

Human LEC/NCC-4 (CCL16)

MBS692056-5x002mg 5x0.02mg
EUR 1725

Recombinant Human LEC/CCL16 protein

CD01396-5ug 5ug
EUR 176
Description: Human CCL16, also called Liver-expressed chemokine (LEC), Monotactin-1 (MTN-1), IL-10-inducible chemokine and so on, is expressed by the CCL16 gene located on the chromosome 17 in humans. The gene encodes a 120 a.a. residue precursor protein with a 23 a.a. residue predicted signal peptide that is cleaved to generate a 97 a.a. residue mature protein. The protein is secreted by the liver, thymus, spleen cells and showing chemotactic activity for lymphocytes and monocytes but it is distantly related to other CC chemokines, exhibiting less than 30 % sequence identity. CCL16 is highly induced by IL-10, IFN-γ and bacterial lipopolysaccharide in monmcytes and signal through CCR1, CCR2, CCR5, and CCR8.

Recombinant Human LEC (CCL16) Protein

PROTO15467-1 20ug
EUR 380.4
Description: LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes but not neutrophils. Recombinant human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

LEC/NCC-4 Human Recombinant

rAP-0241 Inquiry Ask for price

Human LEC Recombinant Protein Lyophilized

IHULECRLY5UG each
EUR 341
Description: Human LEC Recombinant Protein Lyophilized

Human LEC Recombinant Protein Lyophilized

MBS8432637-INQUIRE INQUIRE Ask for price

LEC antibody

70R-LG003 50 ug
EUR 312
Description: Affinity purified Goat polyclonal LEC antibody

LEC antibody

10R-L115A 500 ug
EUR 240
Description: Mouse monoclonal LEC antibody

LEC Antibody

CSB-PA916043XA01DOA-02mg 0.2mg Ask for price
Description: Recombinant Arabidopsis thaliana LEC protein

LEC Antibody

CSB-PA916043XA01DOA-10mg 10mg Ask for price
Description: Recombinant Arabidopsis thaliana LEC protein

LEC antibody

MBS532318-05mg 0.5mg
EUR 370

LEC antibody

MBS532318-5x05mg 5x0.5mg
EUR 1525

LEC antibody

MBS535708-005mg 0.05mg
EUR 465

LEC antibody

MBS535708-5x005mg 5x0.05mg
EUR 1945

Biotinylated Anti-Human LEC Goat Polyclonal Antibody

TA328364 50 µg Ask for price

Recombinant Human LEC/NCC-4 (CCL16)

7-01792 5µg Ask for price

Recombinant Human LEC/NCC-4 (CCL16)

7-01793 20µg Ask for price

Recombinant Human LEC/NCC-4 (CCL16)

7-01794 1mg Ask for price

Recombinant Human LEC/NCC-4 (CCL16)

HECCP-1601 5ug Ask for price

Recombinant Human LEC/NCC-4 (CCL16)

MBS143272-0005mg 0.005mg
EUR 240

Recombinant Human LEC/NCC-4 (CCL16)

MBS143272-002mg 0.02mg
EUR 310

Recombinant Human LEC/NCC-4 (CCL16)

MBS143272-1mg 1mg
EUR 2880

Recombinant Human LEC/NCC-4 (CCL16)

MBS143272-5x1mg 5x1mg
EUR 12630

LEC / CCL16 / HCC4 Monoclonal antibody [Clone: LEC-14]

LEC-14-100ug 100 ug
EUR 141.79
Description: Identify and measure human LEC. Marker for inflammatory processes.

LEC / CCL16 / HCC4 Monoclonal antibody [Clone: LEC-14]

LEC-14-1mg 1 mg
EUR 897.6
Description: Identify and measure human LEC. Marker for inflammatory processes.

LEC / CCL16 / HCC4 Monoclonal antibody [Clone: LEC-14]

LEC-14-500ug 500 ug
EUR 479.6
Description: Identify and measure human LEC. Marker for inflammatory processes.

LEC / CCL16 / HCC4 Monoclonal antibody [Clone: LEC-57]

LEC-57-100ug 100 ug
EUR 141.79
Description: Identify and measure human LEC. Marker for inflammatory processes.

LEC / CCL16 / HCC4 Monoclonal antibody [Clone: LEC-57]

LEC-57-1mg 1 mg
EUR 897.6
Description: Identify and measure human LEC. Marker for inflammatory processes.

LEC / CCL16 / HCC4 Monoclonal antibody [Clone: LEC-57]

LEC-57-500ug 500 ug
EUR 479.6
Description: Identify and measure human LEC. Marker for inflammatory processes.

lec-7 Antibody

CSB-PA600640XA01CXY-02mg 0.2mg Ask for price
Description: Recombinant Caenorhabditis elegans lec-7 protein

lec-7 Antibody

CSB-PA600640XA01CXY-10mg 10mg Ask for price
Description: Recombinant Caenorhabditis elegans lec-7 protein

lec-3 Antibody

CSB-PA601014XA01CXY-02mg 0.2mg Ask for price
Description: Recombinant Caenorhabditis elegans lec-3 protein

lec-3 Antibody

CSB-PA601014XA01CXY-10mg 10mg Ask for price
Description: Recombinant Caenorhabditis elegans lec-3 protein

lec-8 Antibody

CSB-PA222370XA01CXY-02mg 0.2mg Ask for price
Description: Recombinant Caenorhabditis elegans lec-8 protein

lec-8 Antibody

CSB-PA222370XA01CXY-10mg 10mg Ask for price
Description: Recombinant Caenorhabditis elegans lec-8 protein

lec-1 Antibody

CSB-PA330605XA01CXY-02mg 0.2mg Ask for price
Description: Recombinant Caenorhabditis elegans lec-1 protein

lec-1 Antibody

CSB-PA330605XA01CXY-10mg 10mg Ask for price
Description: Recombinant Caenorhabditis elegans lec-1 protein

LEC/CCL16 Matched ELISA Antibody Pair Set, Human

MBS8118261-15Plates 15Plates
EUR 600

LEC/CCL16 Matched ELISA Antibody Pair Set, Human

MBS8118261-5Plates 5Plates
EUR 345

LEC/CCL16 Matched ELISA Antibody Pair Set, Human

MBS8118261-5x15Plates 5x15Plates
EUR 2755

HCC-4, LEC, NCC-4, CCL16, human

RC315-27 5ug
EUR 125.26

Human LEC/NCC-4 (CCL16) Recombinant Protein

100-060 20 µg
EUR 196.35
Description: LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes but not neutrophils. Recombinant human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Human LEC/NCC-4 (CCL16) Recombinant Protein

100-060S 5 µg
EUR 92.4
Description: LEC is a CC chemokine that can signal through the CCR8 and CCR1 receptors. It is expressed in the liver, spleen, and thymus. LEC is chemotactic towards monocytes and lymphocytes but not neutrophils. Recombinant human LEC is an 11.2 kDa protein containing 97 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

LEC (CCL16) (NM_004590) Human Over-expression Lysate

E45H18931-2 20 ug
EUR 395

LEC (CCL16) (NM_004590) Human Over-expression Lysate

LS006360 100ug
EUR 628
Description: Transient overexpression lysate of chemokine (C-C motif) ligand 16 (CCL16)

LEC/CCL16 Protein, Human, Recombinant (His Tag)

E45H52205E1-50 50 ug
EUR 670.31

LEC/CCL16 Protein, Human, Recombinant (His Tag)

MBS8120314-005mg 0.05mg
EUR 340

LEC/CCL16 Protein, Human, Recombinant (His Tag)

MBS8120314-1mg 1mg
EUR 2530

LEC/CCL16 Protein, Human, Recombinant (His Tag)

MBS8120314-5x1mg 5x1mg
EUR 11240

LEC/CCL16 Protein, Human, Recombinant (His Tag)

MBS8120315-005mg 0.05mg
EUR 340

LEC/CCL16 Protein, Human, Recombinant (His Tag)

MBS8120315-5x005mg 5x0.05mg
EUR 1380

CCL16 LEC/NCC-4 Human Recombinant Protein

PROTO15467 Regular: 20ug
EUR 250
Description: CCL16 Human Recombinant produced in E. coli is a non-glycosylated, Polypeptide chain containing 97 amino acids and having a molecular mass of 11.2 kDa. The CCL16 is purified by proprietary chromatographic techniques.

LEC, NCC-4, Human (Liver-Expressed Chemokine)

MBS635010-0005mg 0.005mg
EUR 340

LEC, NCC-4, Human (Liver-Expressed Chemokine)

MBS635010-002mg 0.02mg
EUR 490

LEC, NCC-4, Human (Liver-Expressed Chemokine)

MBS635010-5x002mg 5x0.02mg
EUR 2055

LEC protein

30R-AL013 20 ug
EUR 312
Description: Purified recombinant Human LEC protein

LEC protein

MBS539381-002mg 0.02mg
EUR 465

LEC protein

MBS539381-5x002mg 5x0.02mg
EUR 1945

LEC Chemokine(LEC66) Antibody

BNC800066-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC66), CF680 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC800066-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC66), CF680 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC800067-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC67), CF680 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC800067-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC67), CF680 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC810066-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC66), CF680R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC810066-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC66), CF680R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC810067-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC67), CF680R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC810067-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC67), CF680R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNUM0066-50 50uL
EUR 474
Description: Primary antibody against LEC Chemokine(LEC66), 1mg/mL

LEC Chemokine(LEC67) Antibody

BNUM0067-50 50uL
EUR 474
Description: Primary antibody against LEC Chemokine(LEC67), 1mg/mL

LEC Chemokine(LEC66) Antibody

BNC430066-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC66), CF543 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC430066-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC66), CF543 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC430067-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC67), CF543 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC430067-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC67), CF543 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC470066-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC66), CF647 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC470066-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC66), CF647 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC470067-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC67), CF647 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC470067-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC67), CF647 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC400066-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC66), CF640R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC400066-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC66), CF640R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC400067-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC67), CF640R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC400067-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC67), CF640R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC610066-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC66), CF660R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC610066-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC66), CF660R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC610067-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC67), CF660R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC610067-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC67), CF660R conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC680066-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC66), CF568 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC680066-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC66), CF568 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC680067-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC67), CF568 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC680067-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC67), CF568 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCA0066-250 250uL
EUR 459.6
Description: Primary antibody against LEC Chemokine(LEC66), APC conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCA0067-250 250uL
EUR 459.6
Description: Primary antibody against LEC Chemokine(LEC67), APC conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC880066-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC66), CF488A conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC880066-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC66), CF488A conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC880067-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC67), CF488A conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC880067-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC67), CF488A conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC700066-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC66), CF770 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNC700066-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC66), CF770 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC700067-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC67), CF770 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNC700067-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC67), CF770 conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCH0066-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC66), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCH0066-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC66), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCH0067-100 100uL
EUR 238.8
Description: Primary antibody against LEC Chemokine(LEC67), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCH0067-500 500uL
EUR 652.8
Description: Primary antibody against LEC Chemokine(LEC67), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC66) Antibody

BNCP0066-250 250uL
EUR 459.6
Description: Primary antibody against LEC Chemokine(LEC66), PerCP conjugate, Concentration: 0.1mg/mL

LEC Chemokine(LEC67) Antibody

BNCP0067-250 250uL
EUR 459.6
Description: Primary antibody against LEC Chemokine(LEC67), PerCP conjugate, Concentration: 0.1mg/mL