Tag: biology cells notes
exchange efficiency and stability of bispecific antibodies
Sheathless CE-MS as a tool for monitoring exchange efficiency and stability of bispecific antibodies Bispecific monoclonal antibodies (BsAbs) are receiving great attention due to their extensive benefits as biopharmaceuticals and their involvement in IgG4 mediated autoimmune diseases. While the production of BsAbs is getting more accessible, their analytical characterization remains challenging. We explored the potential of […]
The Role of IgG Subclass in Antibody-Mediated
The Role of IgG Subclass in Antibody-Mediated Protection against Carbapenem-Resistant Klebsiella pneumoniae Monoclonal antibodies (MAbs) have the potential to assist in the battle against multidrug-resistant bacteria such as carbapenem-resistant Klebsiella pneumoniae (CR-Kp). However, the characteristics by which these antibodies (Abs) function, such as the role of antibody subclass, must be determined before such modalities can be carried from […]
Transfer of Proteins From Polyacrylamide Gels to Nitrocellulose Sheets
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications A method has been devised for the electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. The method results in quantitative transfer of ribosomal proteins from gels containing urea. For sodium dodecyl sulfate gels, the original band pattern was […]